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Create a 8-second, high-quality, photorealistic 3D medical animation explaining below-the-knee arterial restenosis and endovascular revascularization in a patient with diabetic chronic limb-threatening ischemia. Begin with an anatomical view of the lower leg and smoothly zoom inside a small infrapopliteal artery. Show advanced atherosclerotic plaque, severe calcification, endothelial injury, and a critically narrowed arterial lumen. Red blood cells move slowly through the stenosis, demonstrating reduced blood flow toward an ischemic foot. Show a thin guidewire and angioplasty catheter advancing through the narrowed tibial artery under fluoroscopic guidance. The guidewire successfully crosses the stenotic or occluded segment. Show balloon angioplasty in cross-section. The balloon gradually inflates, compresses the plaque against the arterial wall, enlarges the lumen, and restores blood flow. Briefly illustrate two treatment approaches: a plain uncoated balloon, POBA, and a drug-coated balloon, DCB, releasing antiproliferative medication into the arterial wall to reduce neointimal hyperplasia. Show the artery several months later. In one segment, smooth-muscle-cell proliferation and neointimal tissue progressively narrow the lumen again, representing restenosis. Contrast this with a successfully treated artery maintaining a wider lumen and improved blood flow. Finish with a clean medical infographic showing blood reaching the foot and the following previous-study metrics: “Standard infrapopliteal angioplasty: approximately 63.1% primary patency at 1 year.” “Repeat revascularization: approximately 18.2% at 1 year.” “Major amputation: approximately 14.9% at 1 year.” “DEBATE-BTK trial: restenosis 27% with DCB versus 74% with conventional balloon angioplasty.” Use anatomically accurate arteries, realistic blood flow, professional hospital-grade medical visualization, smooth camera movement, neutral clinical lighting, dark blue background, subtle red arterial highlights, sharp details, cinematic depth of field, and seamless transitions. Maintain a serious scientific tone. Do not show surgery, open wounds, excessive blood, patient faces, logos, device brands, or exaggerated therapeutic claims.

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"Create a 8-second, high-quality, photorealistic 3D medical animation explaining below-the-…" — AI Video & Prompt | imaginary.app